GITHUB AGENT SKILLS / 技能收录
给你的 AI 助手
装上专业技能
我们从 GitHub 持续收录、审核并分类优质的 Agent Skills，按职业与使用场景整理，复制一行命令即可安装到 Claude Code、Cursor 等智能体。
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按 GitHub Stars 排序的优秀创作者
Microsoft
@microsoft
openclaw
@openclaw
OpenAI
@openai
The Apache Software Foundation
@apache
GitHub
@github
Anthropic
@anthropics
AutoGPT
@Significant-Gravitas
Garry Tan
@garrytan全部 Skills 196852
tooluniverse-chemical-compound-retrieval
Retrieves chemical compound information from PubChem and ChEMBL with disambiguation, cross-referencing, and quality assessment. Creates comprehensive compound profiles with identifiers, properties, bioactivity, and drug information. Use when users need chemical data, drug information, or mention PubChem CID, ChEMBL ID, SMILES, InChI, or compound names.
content-research-writer
Assists in writing high-quality content by conducting research, adding citations, improving hooks, iterating on outlines, and providing real-time feedback on each section. Transforms your writing process from solo effort to collaborative partnership.
tooluniverse-cell-line-profiling
Help researchers select and characterize cancer cell lines for experiments. Given a cancer type, gene of interest, or cell line name, profiles molecular features (mutations, expression, CNV), gene dependencies (CRISPR screens), drug sensitivities (IC50/AUC), and genetic backgrounds using DepMap, Cellosaurus, PharmacoDB, COSMIC, CellMarker, CLUE, and SYNERGxDB. Generates a decision-support report for cell line selection. Use when researchers ask about which cell line to use, cell line characterization, DepMap dependencies, drug sensitivity profiles, or cancer model selection.
connect
Connect Claude to any app. Send emails, create issues, post messages, update databases - take real actions across Gmail, Slack, GitHub, Notion, and 1000+ services.
tooluniverse-cancer-variant-interpretation
Provide comprehensive clinical interpretation of somatic mutations in cancer. Given a gene symbol + variant (e.g., EGFR L858R, BRAF V600E) and optional cancer type, performs multi-database analysis covering clinical evidence (CIViC), mutation prevalence (cBioPortal), therapeutic associations (OpenTargets, ChEMBL, FDA), resistance mechanisms, clinical trials, prognostic impact, and pathway context. Generates an evidence-graded markdown report with actionable recommendations for precision oncology. Use when oncologists, molecular tumor boards, or researchers ask about treatment options for specific cancer mutations, resistance mechanisms, or clinical trial matching.
connect-apps
Connect Claude to external apps like Gmail, Slack, GitHub. Use this skill when the user wants to send emails, create issues, post messages, or take actions in external services.
tooluniverse-cancer-genomics-tcga
TCGA/GDC cancer genomics analysis -- cohort construction, clinical metadata retrieval, somatic mutation profiling, copy number variation analysis, survival analysis, and clinical variant interpretation. Use when users ask about TCGA data, GDC cancer cohorts, somatic mutation frequencies, Kaplan-Meier survival, CNV profiles in cancer, or OncoKB interpretation of cancer variants.
changelog-generator
Automatically creates user-facing changelogs from git commits by analyzing commit history, categorizing changes, and transforming technical commits into clear, customer-friendly release notes. Turns hours of manual changelog writing into minutes of automated generation.
tooluniverse-cancer-classification
Translate free-text tumor descriptions to OncoTree codes, look up cancer subtypes and tissue hierarchies, resolve UMLS/NCI cross-references, and obtain OncoKB-compatible tumor type codes for variant annotation. Use when asked to find the OncoTree code for a tumor type, enumerate subtypes of a cancer, list cancers by tissue of origin, or standardize tumor nomenclature for downstream precision oncology analysis.
tooluniverse-binder-discovery
Discover novel small molecule binders for protein targets using structure-based and ligand-based approaches. Creates actionable reports with candidate compounds, ADMET profiles, and synthesis feasibility. Use when users ask to find small molecules for a target, identify novel binders, perform virtual screening, or need hit-to-lead compound identification.
tooluniverse-antibody-engineering
Comprehensive antibody engineering and optimization for therapeutic development. Covers humanization, affinity maturation, developability assessment, and immunogenicity prediction. Use when asked to optimize antibodies, humanize sequences, or engineer therapeutic antibodies from lead to clinical candidate.
tooluniverse-aging-senescence
Research aging biology, cellular senescence, and longevity using ToolUniverse. Covers senescence markers and pathways, age-related disease genetics, telomere biology, senolytic drug discovery, epigenetic aging clocks, and longevity gene analysis. Integrates GWAS data, gene expression (GTEx age effects), pathway databases, drug repurposing, and literature. Use when asked about aging mechanisms, senescence, senolytics, longevity genes, age-related diseases, or epigenetic clocks.
tooluniverse-adverse-outcome-pathway
Map environmental/industrial chemicals to mechanistic adverse outcome pathways (AOPs) using AOPWiki, quantify toxicological hazard (PubChemTox GHS/carcinogen classification, LD50 values), and link chemical stressors to gene targets and disease endpoints via CTD for regulatory risk assessment. Use when asked about AOP stressor mapping, GHS hazard categories, LD50 data, IARC carcinogen classification, or mechanism-based risk assessment for non-drug chemicals.
skill-creator
Guide for creating effective skills. This skill should be used when users want to create a new skill (or update an existing skill) that extends Codex's capabilities with specialized knowledge, workflows, or tool integrations.
tooluniverse-adverse-event-detection
Detect and analyze adverse drug event signals using FDA FAERS data, drug labels, disproportionality analysis (PRR, ROR, IC), and biomedical evidence. Generates quantitative safety signal scores (0-100) with evidence grading. Use for post-market surveillance, pharmacovigilance, drug safety assessment, adverse event investigation, and regulatory decision support.
tooluniverse-admet-prediction
Comprehensive ADMET (Absorption, Distribution, Metabolism, Excretion, Toxicity) profiling of drug candidates using ADMETAI predictions, SwissADME drug-likeness, PubChemTox experimental toxicity, ChEMBL clinical data, and PubChem properties. Generates a structured ADMET scorecard with pass/fail verdicts per category. Use when asked about drug-likeness, ADMET properties, bioavailability, toxicity prediction, BBB penetration, CYP interactions, pharmacokinetic profiling, Lipinski rule of five, or ADME/PK assessment of a compound.
tooluniverse-acmg-variant-classification
Systematic ACMG/AMP variant classification using ToolUniverse tools. Given a genetic variant (HGVS, rsID, or gene+change), applies all 28 ACMG criteria (PVS1, PS1-4, PM1-6, PP1-5, BA1, BS1-4, BP1-7) through automated database queries and computational predictions. Produces a final 5-tier classification (Pathogenic / Likely Pathogenic / VUS / Likely Benign / Benign) with evidence summary. Use when asked to classify a variant, interpret a VUS, apply ACMG criteria, assess pathogenicity, or determine clinical significance of a germline variant.
swift-protocol-di-testing
Protocol-based dependency injection for testable Swift code — mock file system, network, and external APIs using focused protocols and Swift Testing.