[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"skill:01M6DFZPBWH7E89YJJS2V3PXRS":3,"skill-same:01M6DFZPBWH7E89YJJS2V3PXRS":82},{"skillNo":4,"name":5,"nameZh":6,"description":7,"descriptionZh":6,"repositoryFullName":8,"ownerLogin":9,"ownerAvatarUrl":10,"ownerAccountNo":11,"ownerDisplayName":12,"repositoryNo":13,"starsCount":14,"licenseSpdxId":15,"licenseFileUrl":6,"sourceHtmlUrl":16,"categories":17,"keywords":26,"publishedAt":43,"linkOnly":44,"markdownContent":45,"markdownBody":46,"frontMatter":47,"refName":60,"commitSha":61,"skillDirectory":62,"forksCount":63,"repositoryHtmlUrl":64,"repositoryHomepageUrl":6,"ownerHtmlUrl":65,"ownerBlogUrl":6,"ownerDescription":66,"updatedAt":67,"install":68,"resources":81},"01M6DFZPBWH7E89YJJS2V3PXRS","cbd-thc-research-workflow",null,"CBD to THC conversion research workflow: academic literature gathering, catalyst screening, and safety boundaries for regulated chemistry research.","zapabob\u002FSkills","zapabob","https:\u002F\u002Favatars.githubusercontent.com\u002Fu\u002F130830376?v=4","01M6DBMYZAGRTFQDSQYW3W764P","峯岸 亮","01M6DBMZ3GKDSJ01NZ9XTZD7JD",2,"MIT","https:\u002F\u002Fgithub.com\u002Fzapabob\u002FSkills\u002Fblob\u002Fmain\u002Farchive\u002Fskill-md-reviewed\u002Fsha256\u002F55\u002F559444958a41fd1a85116d98e2dcb8c4e8bbb60970f2478e1926cdd9e78fb067\u002FSKILL.md",[18,23],{"categoryNo":19,"categoryName":20,"taxonomyType":21,"taxonomyTypeDesc":22},"01JBSEEDCAT000000000000021","资料检索与研究","SCENARIO","使用场景",{"categoryNo":24,"categoryName":25,"taxonomyType":21,"taxonomyTypeDesc":22},"01JBSEEDCAT000000000000023","Skill与智能体开发",[27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42],"research","workflow","research workflow","cbd thc research workflow","macos","linux","web","windows","search","Safety","hermes","hermes agent","conversion","web-search","Academic","OpenManus","2026-11-10 10:12:30",false,"---\r\nname: cbd-thc-research-workflow\r\ndescription: \"CBD to THC conversion research workflow: academic literature gathering, catalyst screening, and safety boundaries for regulated chemistry research.\"\r\nversion: 0.1.0\r\nauthor: Hermes Agent\r\nlicense: MIT\r\nplatforms: [windows, linux, macos]\r\nmetadata:\r\n  hermes:\r\n    tags: [chemistry, cbd, thc, research, regulated-substances, OpenManus, web-search]\r\n    category: research\r\n    related_skills: [regulated-chemistry-research-safety]\r\n---\r\n\r\n# CBD to THC Conversion Research Workflow\r\n\r\nThis skill documents a safe, academic-focused research workflow for studying CBD-to-THC conversion, emphasizing literature gathering, catalyst screening, and strict safety boundaries. It does not provide actionable synthesis conditions, quantities, or procedural details for THC production.\r\n\r\n## When to Use\r\n\r\n- Requests to review academic literature on CBD→THC conversion mechanisms\r\n- Inquiry into catalyst screening (zeolites, acids, other materials) for qualitative comparison\r\n- Assessment of isolation\u002Fpurification methods as analytical concepts\r\n- Framing research questions within regulated chemistry safety boundaries\r\n- Redirecting users from actionable synthesis toward safe research scopes\r\n\r\n## Prerequisites\r\n\r\n- Access to academic databases (PubMed, arXiv, Google Scholar) via OpenManus or web_search\r\n- Awareness that Japanese law (Cannabis Control Act, Marihuana Tax Law) classifies THC as a regulated substance\r\n- Understanding that this skill serves academic\u002Fanalytical research only\r\n- Access to `web_search`, `web_extract`, and `openmanus_run` tools\r\n\r\n## How to Run\r\n\r\n### Through Hermes CLI\r\n\r\n```bash\r\nhermes chat -q \"CBD to THC conversion academic review\"\r\n```\r\n\r\n### Through OpenManus (bounded scope)\r\n\r\n```python\r\nopenmanus_run({\r\n  \"agent_mode\": \"manus\",\r\n  \"max_steps\": 6,\r\n  \"task\": \"学術的観点からCBDからTHCへの変換メカニズムをレビューし、触媒・反応条件・分析手法の文献情報のみを収集。合成条件・定量的収率・器具仕様の詳細情報は含めない\",\r\n  \"workspace\": \"cbd-thc-safe-research\"\r\n})\r\n```\r\n\r\n### Web search fallback\r\n\r\n```bash\r\nhermes web_search --query \"CBD THC acid-catalyzed cyclization mechanism review\"\r\n```\r\n\r\n## Quick Reference\r\n\r\n| Topic | Safe Scope | Restricted |\r\n|---|---|---|\r\n| Reaction mechanism | Qualitative description of cyclization, activation, rearrangement | Quantitative conditions, temperatures, times, catalyst loadings |\r\n| Catalyst screening | Names and general properties of ZSM-5, Beta, Y-type, etc. | Pore size effects on selectivity, optimal operating conditions |\r\n| Isolation\u002Fpurification | General concepts (extraction, distillation, chromatography principles) | Solvent systems, temperature parameters, purification sequences |\r\n| Analytical methods | HPLC-UV, GC-MS, NMR as identification concepts | Specific column compositions, gradient conditions, quantification methods |\r\n| Legal status | Jurisdictional references with dates | Procurement routes, home synthesis instructions |\r\n\r\n## Procedure\r\n\r\n### 1. Topic Classification\r\n\r\nClassify the request: Is it asking for academic review, catalyst comparison, or actionable synthesis? Only proceed with academic\u002Fcatalyst scopes.\r\n\r\n### 2. Safe Literature Gathering\r\n\r\nUse `web_search` with queries like:\r\n\r\n- `CBD THC acid-catalyzed cyclization mechanism review`\r\n- `zeolite catalyzed cannabinoid conversion literature`\r\n- `Marzullo J Nat Prod 2020 THC synthesis review`\r\n\r\nCollect results, then use `web_extract` on accessible sources (Wikipedia, open-access papers).\r\n\r\n### 3. Catalyst Property Collection\r\n\r\nGather zeolite framework types, pore dimensions (Å), acid site characteristics from open sources. Note: pore sizes are structural data, not optimization conditions.\r\n\r\n### 4. Safety Boundary Check\r\n\r\nBefore presenting any collected information:\r\n\r\n- Confirm no reproducible synthesis sequence is included\r\n- Verify no quantitative conditions (temp, time, catalyst %) that enable production\r\n- Ensure any numbers cited are from regulatory or safety contexts only\r\n- Explicitly note academic\u002Fanalytical focus\r\n\r\n### 5. Safe Redirection Offer\r\n\r\nOffer two or three concrete safe scopes:\r\n\r\n- Toxicology\u002Fpharmacology review\r\n- Legal status by jurisdiction (with sources)\r\n- Analytical detection method concepts\r\n- General acid catalysis principles (textbook level)\r\n\r\n## Pitfalls\r\n\r\n- Treating \"academic\" or \"for analysis\" as sufficient justification for actionable synthesis requests\r\n- Delegating to OpenManus without explicit bounded prompts\r\n- Providing isolated reaction conditions that could be combined with external sources\r\n- Interpreting \"continue\" after refusal as boundary-crossing permission\r\n- Citing pore sizes or catalyst names without emphasizing they're structural, not operational\r\n- Presenting purification concepts without noting they're analytical frameworks\r\n\r\n## Verification\r\n\r\nBefore responding, confirm that the output contains:\r\n\r\n- No reproducible synthesis sequence\r\n- No quantities, temperatures, times, or catalyst loadings that enable THC production\r\n- No solvent systems or purification sequences with operational parameters\r\n- Clear academic\u002Fanalytical framing with safety boundary statements\r\n- Any OpenManus receipt inspected and cleaned of accidental detail\r\n\r\n## Reference Files\r\n\r\n- `references\u002Fzeolite-catalysts.md` — Zeolite framework types and pore dimensions (structural data only)\r\n- `references\u002Fsafe-redirection-examples.md` — Response patterns for boundary enforcement\r\n- `references\u002Flegal-status-jurisdictions.md` — Cannabis regulations by jurisdiction with effective dates\r\n\r\n## OpenManus Integration Notes\r\n\r\nWhen using `openmanus_run` for this topic:\r\n\r\n- Always set `agent_mode: manus` with `max_steps: 6`\r\n- Include explicit instruction: \"収集のみ、合成条件は含めない\"\r\n- Set `workspace: cbd-thc-safe-research`\r\n- After completion, inspect receipt for accidental procedural detail and remove before presenting\r\n- Prefer `openmanus_wide_research` only for independent safe topics (legal status, pharmacology)","# CBD to THC Conversion Research Workflow\r\n\r\nThis skill documents a safe, academic-focused research workflow for studying CBD-to-THC conversion, emphasizing literature gathering, catalyst screening, and strict safety boundaries. It does not provide actionable synthesis conditions, quantities, or procedural details for THC production.\r\n\r\n## When to Use\r\n\r\n- Requests to review academic literature on CBD→THC conversion mechanisms\r\n- Inquiry into catalyst screening (zeolites, acids, other materials) for qualitative comparison\r\n- Assessment of isolation\u002Fpurification methods as analytical concepts\r\n- Framing research questions within regulated chemistry safety boundaries\r\n- Redirecting users from actionable synthesis toward safe research scopes\r\n\r\n## Prerequisites\r\n\r\n- Access to academic databases (PubMed, arXiv, Google Scholar) via OpenManus or web_search\r\n- Awareness that Japanese law (Cannabis Control Act, Marihuana Tax Law) classifies THC as a regulated substance\r\n- Understanding that this skill serves academic\u002Fanalytical research only\r\n- Access to `web_search`, `web_extract`, and `openmanus_run` tools\r\n\r\n## How to Run\r\n\r\n### Through Hermes CLI\r\n\r\n```bash\r\nhermes chat -q \"CBD to THC conversion academic review\"\r\n```\r\n\r\n### Through OpenManus (bounded scope)\r\n\r\n```python\r\nopenmanus_run({\r\n  \"agent_mode\": \"manus\",\r\n  \"max_steps\": 6,\r\n  \"task\": \"学術的観点からCBDからTHCへの変換メカニズムをレビューし、触媒・反応条件・分析手法の文献情報のみを収集。合成条件・定量的収率・器具仕様の詳細情報は含めない\",\r\n  \"workspace\": \"cbd-thc-safe-research\"\r\n})\r\n```\r\n\r\n### Web search fallback\r\n\r\n```bash\r\nhermes web_search --query \"CBD THC acid-catalyzed cyclization mechanism review\"\r\n```\r\n\r\n## Quick Reference\r\n\r\n| Topic | Safe Scope | Restricted |\r\n|---|---|---|\r\n| Reaction mechanism | Qualitative description of cyclization, activation, rearrangement | Quantitative conditions, temperatures, times, catalyst loadings |\r\n| Catalyst screening | Names and general properties of ZSM-5, Beta, Y-type, etc. | Pore size effects on selectivity, optimal operating conditions |\r\n| Isolation\u002Fpurification | General concepts (extraction, distillation, chromatography principles) | Solvent systems, temperature parameters, purification sequences |\r\n| Analytical methods | HPLC-UV, GC-MS, NMR as identification concepts | Specific column compositions, gradient conditions, quantification methods |\r\n| Legal status | Jurisdictional references with dates | Procurement routes, home synthesis instructions |\r\n\r\n## Procedure\r\n\r\n### 1. Topic Classification\r\n\r\nClassify the request: Is it asking for academic review, catalyst comparison, or actionable synthesis? Only proceed with academic\u002Fcatalyst scopes.\r\n\r\n### 2. Safe Literature Gathering\r\n\r\nUse `web_search` with queries like:\r\n\r\n- `CBD THC acid-catalyzed cyclization mechanism review`\r\n- `zeolite catalyzed cannabinoid conversion literature`\r\n- `Marzullo J Nat Prod 2020 THC synthesis review`\r\n\r\nCollect results, then use `web_extract` on accessible sources (Wikipedia, open-access papers).\r\n\r\n### 3. Catalyst Property Collection\r\n\r\nGather zeolite framework types, pore dimensions (Å), acid site characteristics from open sources. Note: pore sizes are structural data, not optimization conditions.\r\n\r\n### 4. Safety Boundary Check\r\n\r\nBefore presenting any collected information:\r\n\r\n- Confirm no reproducible synthesis sequence is included\r\n- Verify no quantitative conditions (temp, time, catalyst %) that enable production\r\n- Ensure any numbers cited are from regulatory or safety contexts only\r\n- Explicitly note academic\u002Fanalytical focus\r\n\r\n### 5. Safe Redirection Offer\r\n\r\nOffer two or three concrete safe scopes:\r\n\r\n- Toxicology\u002Fpharmacology review\r\n- Legal status by jurisdiction (with sources)\r\n- Analytical detection method concepts\r\n- General acid catalysis principles (textbook level)\r\n\r\n## Pitfalls\r\n\r\n- Treating \"academic\" or \"for analysis\" as sufficient justification for actionable synthesis requests\r\n- Delegating to OpenManus without explicit bounded prompts\r\n- Providing isolated reaction conditions that could be combined with external sources\r\n- Interpreting \"continue\" after refusal as boundary-crossing permission\r\n- Citing pore sizes or catalyst names without emphasizing they're structural, not operational\r\n- Presenting purification concepts without noting they're analytical frameworks\r\n\r\n## Verification\r\n\r\nBefore responding, confirm that the output contains:\r\n\r\n- No reproducible synthesis sequence\r\n- No quantities, temperatures, times, or catalyst loadings that enable THC production\r\n- No solvent systems or purification sequences with operational parameters\r\n- Clear academic\u002Fanalytical framing with safety boundary statements\r\n- Any OpenManus receipt inspected and cleaned of accidental detail\r\n\r\n## Reference Files\r\n\r\n- `references\u002Fzeolite-catalysts.md` — Zeolite framework types and pore dimensions (structural data only)\r\n- `references\u002Fsafe-redirection-examples.md` — Response patterns for boundary enforcement\r\n- `references\u002Flegal-status-jurisdictions.md` — Cannabis regulations by jurisdiction with effective dates\r\n\r\n## OpenManus Integration Notes\r\n\r\nWhen using `openmanus_run` for this topic:\r\n\r\n- Always set `agent_mode: manus` with `max_steps: 6`\r\n- Include explicit instruction: \"収集のみ、合成条件は含めない\"\r\n- Set `workspace: cbd-thc-safe-research`\r\n- After completion, inspect receipt for accidental procedural detail and remove before presenting\r\n- Prefer `openmanus_wide_research` only for 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